No safety issues were recognized in these scholarly studies, the FDA said. Coagadex is manufactured by Bio Items Laboratory Ltd., located in the United Kingdom.. Coagadex Approved for Rare Clotting Disorder: – WEDNESDAY, Oct. 21, 2015 – – Coagadex has been approved by the U.S. Food and Medication Administration because the first coagulation element replacement therapy for those who have a rare blood disorder referred to as hereditary Factor X insufficiency. The Element X protein normally helps blood coagulum. But among people who have the inherited disorder, the blood does clot, which can result in dangerous bleeding episodes. Traditional treatments derive from plasma-derived products containing supplement K-dependent proteins to stem or prevent bleeding, the company said in a news release.But, should you choose to perform a peel, always follow through with an excellent lotion for night and morning. Is your skin looking radiant? Uncover the natural skin care & organic beauty products as recommended by certified dermatologist at Kaya, among the global skin clinics across UAE, Saudi Arabia & Oman. At Kaya, skincare is certainly result oriented, driven by expert dermatologists and epidermis practitioners, delivered in private, Zen like environment, after understanding the specific requirements of your skin.