The scholarly study findings were published Sept. 10 in the American Center Association journal Arteriosclerosis, Vascular and Thrombosis Biology.. Too Much, INADEQUATE Sleep May Damage the Heart: – THURSDAY, Sept. 10, 2015 – – Otherwise healthful people who have poor sleep habits may be placing themselves at risk for early indications of heart disease, a fresh study suggests. Folks who get too much or too little sleep – – or insufficient quality rest – – will suffer from stiffened arteries and calcium deposits on the walls of their major arteries, said study lead author Dr. Chan-Won Kim. Coronary calcium develops way before heart attack symptoms occur, and a greater amount of calcium in the coronary arteries predicts upcoming development of cardiovascular disease, said Kim, a clinical associate professor in the guts for Cohort Studies at Kangbuk Samsung Medical center in Seoul, South Korea.Secondary endpoints included evaluation of BMD at other sites, fractures, changes in bone turnover markers and general safety. The incidence of adverse events was comparable between organizations. There is no long-term effect on renal function or upsurge in risk of osteonecrosis of the jaw or atrial fibrillation. Aclasta provides year-long bisphosphonate compliance with an individual infusion. Aclasta may be the only yearly treatment authorized in US and EU to lessen the risk of fractures in areas of the body typically suffering from osteoporosis, like the hip, backbone and non-spine . Additionally, additionally it is the only proven therapy to lessen new clinical fracture and all-trigger mortality after a recently available low trauma hip fracture.